GNU/Hurd support has been integrated in Guix.

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QEMU Image

There is a QEMU image with Guix GNU/Hurd pre-installed available at https://ci.guix.gnu.org/search/latest/image?query=spec:images+status:success+system:x86_64-linux+hurd-barebones.qcow2.

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Documentation

As Hurd support is integrated in Guix, the official documentation (https://guix.gnu.org/en/manual/devel/) also works for Hurd.

Guix has even support in its configuration language for creating Hurd VMs from a running Guix system (https://guix.gnu.org/en/manual/devel/en/guix.html#The-Hurd-in-a-Virtual-Machine).

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Status

At the time of writing, the official Guix manual says that "This configuration is experimental and under development. The easiest way for you to give it a try is by setting up an instance of hurd-vm-service-type on your GNU/Linux machine (see hurd-vm-service-type). See Contributing, on how to help!" (https://guix.gnu.org/en/manual/devel/en/guix.html#GNU-Distribution).